β-Amyloid (1-42), rat TFA

CAS No. ——

β-Amyloid (1-42), rat TFA( —— )

Catalog No. M30036 CAS No. ——

β-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    β-Amyloid (1-42), rat TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    β-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.
  • Description
    β-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.(In Vitro):β-Amyloid (1-42), rat shows cytotoxic effect on the hippocampal slices at 20 μM. β-Amyloid (1-42), rat causes morphological changes in NGF-induced PC12 cells, induces formed cell processes to retract in differentiated cells and affect the expression of exons 2/3 in both undifferentiated and differentiated cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Amyloid-β
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    4532.04
  • Molecular Formula
    C199H307N53O59S.C2HF3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (22.07 mM; Need ultrasonic);H2O : < 0.1 mg/mL (insoluble)
  • SMILES
    ——
  • Chemical Name
    Sequence:Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Mozes E, et al. A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays. Brain Res Bull. 2012 Apr 10;87(6):521-5.
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